PFKP-PSG1 Fusion FISH Probe
The PFKP-PSG1 Fusion FISH Probe is used to confirm a fusion of the PFKP and PSG1 genes. The fusion of the PFKP and PSG1 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PFKP-PSG1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-RERE | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-REOR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-REGO | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-REGR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-REAQ | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-ORRE | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-OROR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-ORGO | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GORE | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GOOR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GOGO | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GOGR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GRRE | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GROR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GRGO | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GRGR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-AQRE | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-AQOR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-AQGO | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-AQGR | 20 (40 μL) | 200 μL |
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| PFKP-PSG1-20-AQAQ | 20 (40 μL) | 200 μL |
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PFKP Gene Summary
This gene encodes a member of the phosphofructokinase A protein family. The encoded enzyme is the platelet-specific isoform of phosphofructokinase and plays a key role in glycolysis regulation. This gene may play a role in metabolic reprogramming in some cancers, including clear cell renal cell carcinomas, and cancer of the bladder, breast, and lung. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2016]
Gene Name: Phosphofructokinase, Platelet
Chromosome: CHR10: 3109711 -3178997
Locus: 10p15.2
PSG1 Gene Summary
The human placenta is a multihormonal endocrine organ that produces hormones, enzymes, and other molecules that support fetal survival and development. Pregnancy-specific beta-1-glycoprotein (PSBG, PSG) is a major product of the syncytiotrophoblast, reaching concentrations of 100 to 290 mg/l at term in the serum of pregnant women (Horne et al., 1976 [PubMed 971765]). PSG is a member of the immunoglobulin (Ig) superfamily (Watanabe and Chou, 1988 [PubMed 3257488]; Streydio et al., 1988 [PubMed 3260773]).[supplied by OMIM, Oct 2009]
Gene Name: Pregnancy Specific Beta-1-glycoprotein 1
Chromosome: CHR19: 43370612 -43383871
Locus: 19q13.2
Gene Diseases
The PFKP PSG1 Fusion has been associated with the following diseases:
| Disease Name |
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| Bladder Urothelial Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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