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PGAP3-STARD3 Fusion FISH Probe

The PGAP3-STARD3 Fusion FISH Probe is used to confirm a fusion of the PGAP3 and STARD3 genes. The fusion of the PGAP3 and STARD3 genes has been associated with Bladder Urothelial Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PGAP3-STARD3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PGAP3-STARD3-20-RERE 20 (40 μL) 200 μL
PGAP3-STARD3-20-REOR 20 (40 μL) 200 μL
PGAP3-STARD3-20-REGO 20 (40 μL) 200 μL
PGAP3-STARD3-20-REGR 20 (40 μL) 200 μL
PGAP3-STARD3-20-REAQ 20 (40 μL) 200 μL
PGAP3-STARD3-20-ORRE 20 (40 μL) 200 μL
PGAP3-STARD3-20-OROR 20 (40 μL) 200 μL
PGAP3-STARD3-20-ORGO 20 (40 μL) 200 μL
PGAP3-STARD3-20-ORAQ 20 (40 μL) 200 μL
PGAP3-STARD3-20-GORE 20 (40 μL) 200 μL
PGAP3-STARD3-20-GOOR 20 (40 μL) 200 μL
PGAP3-STARD3-20-GOGO 20 (40 μL) 200 μL
PGAP3-STARD3-20-GOGR 20 (40 μL) 200 μL
PGAP3-STARD3-20-GOAQ 20 (40 μL) 200 μL
PGAP3-STARD3-20-GRRE 20 (40 μL) 200 μL
PGAP3-STARD3-20-GROR 20 (40 μL) 200 μL
PGAP3-STARD3-20-GRGO 20 (40 μL) 200 μL
PGAP3-STARD3-20-GRGR 20 (40 μL) 200 μL
PGAP3-STARD3-20-GRAQ 20 (40 μL) 200 μL
PGAP3-STARD3-20-AQRE 20 (40 μL) 200 μL
PGAP3-STARD3-20-AQOR 20 (40 μL) 200 μL
PGAP3-STARD3-20-AQGO 20 (40 μL) 200 μL
PGAP3-STARD3-20-AQGR 20 (40 μL) 200 μL
PGAP3-STARD3-20-AQAQ 20 (40 μL) 200 μL

STARD3 Gene Summary

This gene encodes a member of a subfamily of lipid trafficking proteins that are characterized by a C-terminal steroidogenic acute regulatory domain and an N-terminal metastatic lymph node 64 domain. The encoded protein localizes to the membranes of late endosomes and may be involved in exporting cholesterol. Alternative splicing results in multiple transcript variants.[provided by RefSeq, Oct 2009]

Gene Name: StAR Related Lipid Transfer Domain Containing 3

Chromosome: CHR17: 37793332 -37820454

Locus: 17q12

PGAP3 Gene Summary

This gene encodes a glycosylphosphatidylinositol (GPI)-specific phospholipase that primarily localizes to the Golgi apparatus. This ubiquitously expressed gene is predicted to encode a seven-transmembrane protein that removes unsaturated fatty acids from the sn-2 position of GPI. The remodeling of the constituent fatty acids on GPI is thought to be important for the proper association between GPI-anchored proteins and lipid rafts. The tethering of proteins to plasma membranes via posttranslational GPI-anchoring is thought to play a role in protein sorting and trafficking. Mutations in this gene cause an autosomal recessive form of neurologic hyperphosphatasia with cognitive disability (HPMRS4). Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2017]

Gene Name: Post-GPI Attachment To Proteins 3

Chromosome: CHR17: 37827374 -37844310

Locus: 17q12

Gene Diseases

The PGAP3 STARD3 Fusion has been associated with the following diseases:

Disease Name
Bladder Urothelial Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.