PHF11-SETDB2 Fusion FISH Probe
The PHF11-SETDB2 Fusion FISH Probe is used to confirm a fusion of the PHF11 and SETDB2 genes. The fusion of the PHF11 and SETDB2 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHF11-SETDB2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-RERE | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-REOR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-REGO | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-REGR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-REAQ | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-ORRE | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-OROR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-ORGO | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GORE | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GOOR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GOGO | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GOGR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GRRE | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GROR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GRGO | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GRGR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-AQRE | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-AQOR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-AQGO | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-AQGR | 20 (40 μL) | 200 μL |
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| PHF11-SETDB2-20-AQAQ | 20 (40 μL) | 200 μL |
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PHF11 Gene Summary
This gene encodes a protein containing a PHD (plant homeodomain) type zinc finger. This gene has been identified in some studies as a candidate gene for asthma. Naturally-occurring readthrough transcription may occur from the upstream SETDB2 (SET domain bifurcated 2) gene to this locus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: PHD Finger Protein 11
Chromosome: CHR13: 50069800 -50103117
Locus: 13q14.2
SETDB2 Gene Summary
This gene encodes a member of a family of proteins that contain a methyl-CpG-binding domain (MBD) and a SET domain and function as histone methyltransferases. This protein is recruited to heterochromatin and plays a role in the regulation of chromosome segregation. This region is commonly deleted in chronic lymphocytic leukemia. Naturally-occuring readthrough transcription occurs from this gene to the downstream PHF11 (PHD finger protein 11) gene. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2016]
Gene Name: SET Domain Bifurcated 2
Chromosome: CHR13: 50018428 -50069139
Locus: 13q14.2
Gene Diseases
The PHF11 SETDB2 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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