PHF15-UBE2B Fusion FISH Probe
The PHF15-UBE2B Fusion FISH Probe is used to confirm a fusion of the PHF15 and UBE2B genes. The fusion of the PHF15 and UBE2B genes has been associated with Liver Hepatocellular Carcinoma, and Adrenocortical Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| PHF15-UBE2B-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-RERE | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-REOR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-REGO | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-REGR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-OROR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GORE | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GROR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| PHF15-UBE2B-20-AQAQ | 20 (40 μL) | 200 μL |
|
UBE2B Gene Summary
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is required for post-replicative DNA damage repair. Its protein sequence is 100% identical to the mouse, rat, and rabbit homologs, which indicates that this enzyme is highly conserved in eukaryotic evolution. [provided by RefSeq, Jul 2008]
Gene Name: Ubiquitin Conjugating Enzyme E2 B
Chromosome: CHR5: 133706869 -133727799
Locus: 5q31.1
Gene Diseases
The PHF15 UBE2B Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Liver Hepatocellular Carcinoma |
| Adrenocortical Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|