PHGDH-ANXA1 Fusion FISH Probe
The PHGDH-ANXA1 Fusion FISH Probe is used to confirm a fusion of the PHGDH and ANXA1 genes. The fusion of the PHGDH and ANXA1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PHGDH-ANXA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-RERE | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-REOR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-REGO | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-REGR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-REAQ | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-ORRE | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-OROR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-ORGO | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GORE | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GOOR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GOGO | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GOGR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GRRE | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GROR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GRGO | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GRGR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-AQRE | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-AQOR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-AQGO | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-AQGR | 20 (40 μL) | 200 μL |
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| PHGDH-ANXA1-20-AQAQ | 20 (40 μL) | 200 μL |
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ANXA1 Gene Summary
This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]
Gene Name: Annexin A1
Chromosome: CHR9: 75766780 -75785307
Locus: 9q21.13
PHGDH Gene Summary
This gene encodes the enzyme which is involved in the early steps of L-serine synthesis in animal cells. L-serine is required for D-serine and other amino acid synthesis. The enzyme requires NAD/NADH as a cofactor and forms homotetramers for activity. Mutations in this gene have been found in a family with congenital microcephaly, psychomotor retardation and other symptoms. Multiple alternatively spliced transcript variants have been found, however the full-length nature of most are not known. [provided by RefSeq, Aug 2011]
Gene Name: Phosphoglycerate Dehydrogenase
Chromosome: CHR1: 120254418 -120286849
Locus: 1p12
Gene Diseases
The PHGDH ANXA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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