PI4KA-SNAP29 Fusion FISH Probe
The PI4KA-SNAP29 Fusion FISH Probe is used to confirm a fusion of the PI4KA and SNAP29 genes. The fusion of the PI4KA and SNAP29 genes has been associated with Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PI4KA-SNAP29-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-RERE | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-REOR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-REGO | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-REGR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-REAQ | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-ORRE | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-OROR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-ORGO | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-ORAQ | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GORE | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GOOR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GOGO | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GOGR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GOAQ | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GRRE | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GROR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GRGO | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GRGR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-GRAQ | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-AQRE | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-AQOR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-AQGO | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-AQGR | 20 (40 μL) | 200 μL |
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| PI4KA-SNAP29-20-AQAQ | 20 (40 μL) | 200 μL |
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PI4KA Gene Summary
This gene encodes a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine. [provided by RefSeq, Sep 2014]
Gene Name: Phosphatidylinositol 4-kinase Alpha
Chromosome: CHR22: 21061978 -21213070
Locus: 22q11.21
SNAP29 Gene Summary
This gene, a member of the SNAP25 gene family, encodes a protein involved in multiple membrane trafficking steps. Two other members of this gene family, SNAP23 and SNAP25, encode proteins that bind a syntaxin protein and mediate synaptic vesicle membrane docking and fusion to the plasma membrane. The protein encoded by this gene binds tightly to multiple syntaxins and is localized to intracellular membrane structures rather than to the plasma membrane. While the protein is mostly membrane-bound, a significant fraction of it is found free in the cytoplasm. Use of multiple polyadenylation sites has been noted for this gene. [provided by RefSeq, Jul 2008]
Gene Name: Synaptosome Associated Protein 29
Chromosome: CHR22: 21213291 -21245501
Locus: 22q11.21
Gene Diseases
The PI4KA SNAP29 Fusion has been associated with the following diseases:
| Disease Name |
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| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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