PITPNA-LLGL2 Fusion FISH Probe
The PITPNA-LLGL2 Fusion FISH Probe is used to confirm a fusion of the PITPNA and LLGL2 genes. The fusion of the PITPNA and LLGL2 genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PITPNA-LLGL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-RERE | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-REOR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-REGO | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-REGR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-REAQ | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-ORRE | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-OROR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-ORGO | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GORE | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GOOR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GOGO | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GOGR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GRRE | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GROR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GRGO | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GRGR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-AQRE | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-AQOR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-AQGO | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-AQGR | 20 (40 μL) | 200 μL |
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| PITPNA-LLGL2-20-AQAQ | 20 (40 μL) | 200 μL |
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LLGL2 Gene Summary
The lethal (2) giant larvae protein of Drosophila plays a role in asymmetric cell division, epithelial cell polarity, and cell migration. This human gene encodes a protein similar to lethal (2) giant larvae of Drosophila. In fly, the protein's ability to localize cell fate determinants is regulated by the atypical protein kinase C (aPKC). In human, this protein interacts with aPKC-containing complexes and is cortically localized in mitotic cells. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
Gene Name: LLGL2, Scribble Cell Polarity Complex Component
Chromosome: CHR17: 73521782 -73571290
Locus: 17q25.1
PITPNA Gene Summary
This gene encodes a member of a family of lipid-binding proteins that transfer molecules of phosphatidylinositol or phosphatidylcholine between membrane surfaces. The protein is implicated in phospholipase C signaling and in the production of phosphatidylinositol 3,4,5-trisphosphate (PIP3) by phosphoinositide-3-kinase.[provided by RefSeq, Sep 2009]
Gene Name: Phosphatidylinositol Transfer Protein Alpha
Chromosome: CHR17: 1421282 -1466110
Locus: 17p13.3
Gene Diseases
The PITPNA LLGL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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