PITPNM1-NUMA1 Fusion FISH Probe
The PITPNM1-NUMA1 Fusion FISH Probe is used to confirm a fusion of the PITPNM1 and NUMA1 genes. The fusion of the PITPNM1 and NUMA1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PITPNM1-NUMA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-RERE | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-REOR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-REGO | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-REGR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-REAQ | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-ORRE | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-OROR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-ORGO | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GORE | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GOOR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GOGO | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GOGR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GRRE | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GROR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GRGO | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GRGR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-AQRE | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-AQOR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-AQGO | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-AQGR | 20 (40 μL) | 200 μL |
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| PITPNM1-NUMA1-20-AQAQ | 20 (40 μL) | 200 μL |
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NUMA1 Gene Summary
This gene encodes a large protein that forms a structural component of the nuclear matrix. The encoded protein interacts with microtubules and plays a role in the formation and organization of the mitotic spindle during cell division. Chromosomal translocation of this gene with the RARA (retinoic acid receptor, alpha) gene on chromosome 17 have been detected in patients with acute promyelocytic leukemia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2013]
Gene Name: Nuclear Mitotic Apparatus Protein 1
Chromosome: CHR11: 71713910 -71791573
Locus: 11q13.4
PITPNM1 Gene Summary
PITPNM1 belongs to a family of membrane-associated phosphatidylinositol transfer domain-containing proteins that share homology with the Drosophila retinal degeneration B (rdgB) protein (Ocaka et al., 2005 [PubMed 15627748]).[supplied by OMIM, Mar 2008]
Gene Name: Phosphatidylinositol Transfer Protein Membrane Associated 1
Chromosome: CHR11: 67259238 -67272843
Locus: 11q13.2
Gene Diseases
The PITPNM1 NUMA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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