PKM2-USP7 Fusion FISH Probe
The PKM2-USP7 Fusion FISH Probe is used to confirm a fusion of the PKM2 and USP7 genes. The fusion of the PKM2 and USP7 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PKM2-USP7-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-RERE | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-REOR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-REGO | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-REGR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-REAQ | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-ORRE | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-OROR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-ORGO | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-ORAQ | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GORE | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GOOR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GOGO | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GOGR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GOAQ | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GRRE | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GROR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GRGO | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GRGR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-GRAQ | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-AQRE | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-AQOR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-AQGO | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-AQGR | 20 (40 μL) | 200 μL |
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| PKM2-USP7-20-AQAQ | 20 (40 μL) | 200 μL |
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USP7 Gene Summary
The protein encoded by this gene belongs to the peptidase C19 family, which includes ubiquitinyl hydrolases. This protein deubiquitinates target proteins such as p53 (a tumor suppressor protein) and WASH (essential for endosomal protein recycling), and regulates their activities by counteracting the opposing ubiquitin ligase activity of proteins such as HDM2 and TRIM27, involved in the respective process. Mutations in this gene have been implicated in a neurodevelopmental disorder. [provided by RefSeq, Mar 2016]
Gene Name: Ubiquitin Specific Peptidase 7
Chromosome: CHR16: 8985950 -9057341
Locus: 16p13.2
Gene Diseases
The PKM2 USP7 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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