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PLA2G2A-FBLN1 Fusion FISH Probe

The PLA2G2A-FBLN1 Fusion FISH Probe is used to confirm a fusion of the PLA2G2A and FBLN1 genes. The fusion of the PLA2G2A and FBLN1 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PLA2G2A-FBLN1-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-RERE 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-REOR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-REGO 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-REGR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-REAQ 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-ORRE 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-OROR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-ORGO 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-ORAQ 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GORE 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GOOR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GOGO 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GOGR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GOAQ 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GRRE 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GROR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GRGO 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GRGR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-GRAQ 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-AQRE 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-AQOR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-AQGO 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-AQGR 20 (40 μL) 200 μL
PLA2G2A-FBLN1-20-AQAQ 20 (40 μL) 200 μL

FBLN1 Gene Summary

Fibulin 1 is a secreted glycoprotein that becomes incorporated into a fibrillar extracellular matrix. Calcium-binding is apparently required to mediate its binding to laminin and nidogen. It mediates platelet adhesion via binding fibrinogen. Four splice variants which differ in the 3' end have been identified. Each variant encodes a different isoform, but no functional distinctions have been identified among the four variants. [provided by RefSeq, Jul 2008]

Gene Name: Fibulin 1

Chromosome: CHR22: 45898718 -45997014

Locus: 22q13.31

PLA2G2A Gene Summary

The protein encoded by this gene is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.[provided by RefSeq, Sep 2009]

Gene Name: Phospholipase A2 Group IIA

Chromosome: CHR1: 20301923 -20306932

Locus: 1p36.13

Gene Diseases

The PLA2G2A FBLN1 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.