PLAU-ZMAT2 Fusion FISH Probe
The PLAU-ZMAT2 Fusion FISH Probe is used to confirm a fusion of the PLAU and ZMAT2 genes. The fusion of the PLAU and ZMAT2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLAU-ZMAT2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-RERE | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-REOR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-REGO | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-REGR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-REAQ | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-ORRE | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-OROR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-ORGO | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GORE | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GOOR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GOGO | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GOGR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GRRE | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GROR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GRGO | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GRGR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-AQRE | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-AQOR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-AQGO | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-AQGR | 20 (40 μL) | 200 μL |
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| PLAU-ZMAT2-20-AQAQ | 20 (40 μL) | 200 μL |
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PLAU Gene Summary
This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Gene Name: Plasminogen Activator, Urokinase
Chromosome: CHR10: 75670861 -75677258
Locus: 10q22.2
ZMAT2 Gene Summary
The Zinc Finger Matrin-type 2 (ZMAT2) gene is located on chr5 :140080031-140086239 at 5q31.3.
Gene Name: Zinc Finger Matrin-type 2
Chromosome: CHR5: 140080031 -140086239
Locus: 5q31.3
Gene Diseases
The PLAU ZMAT2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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