PLCD4-VIL1 Fusion FISH Probe
The PLCD4-VIL1 Fusion FISH Probe is used to confirm a fusion of the PLCD4 and VIL1 genes. The fusion of the PLCD4 and VIL1 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLCD4-VIL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-RERE | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-REOR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-REGO | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-REGR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-OROR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GORE | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GROR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLCD4-VIL1-20-AQAQ | 20 (40 μL) | 200 μL |
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VIL1 Gene Summary
This gene encodes a member of a family of calcium-regulated actin-binding proteins. This protein represents a dominant part of the brush border cytoskeleton which functions in the capping, severing, and bundling of actin filaments. Two mRNAs of 2.7 kb and 3.5 kb have been observed; they result from utilization of alternate poly-adenylation signals present in the terminal exon. [provided by RefSeq, Jul 2008]
Gene Name: Villin 1
Chromosome: CHR2: 219283837 -219314248
Locus: 2q35
PLCD4 Gene Summary
This gene encodes a member of the delta class of phospholipase C enzymes. Phospholipase C enzymes play a critical role in many cellular processes by hydrolyzing phosphatidylinositol 4,5-bisphosphate into two intracellular second messengers, inositol 1,4,5-trisphosphate and diacylglycerol. Expression of this gene may be a marker for cancer. [provided by RefSeq, Jan 2011]
Gene Name: Phospholipase C Delta 4
Chromosome: CHR2: 219472487 -219501909
Locus: 2q35
Gene Diseases
The PLCD4 VIL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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