PLEKHG1-GJA1 Fusion FISH Probe
The PLEKHG1-GJA1 Fusion FISH Probe is used to confirm a fusion of the PLEKHG1 and GJA1 genes. The fusion of the PLEKHG1 and GJA1 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLEKHG1-GJA1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-RERE | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-REOR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-REGO | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-REGR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-OROR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GORE | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GROR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLEKHG1-GJA1-20-AQAQ | 20 (40 μL) | 200 μL |
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GJA1 Gene Summary
This gene is a member of the connexin gene family. The encoded protein is a component of gap junctions, which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell. The encoded protein is the major protein of gap junctions in the heart that are thought to have a crucial role in the synchronized contraction of the heart and in embryonic development. A related intronless pseudogene has been mapped to chromosome 5. Mutations in this gene have been associated with oculodentodigital dysplasia, autosomal recessive craniometaphyseal dysplasia and heart malformations. [provided by RefSeq, May 2014]
Gene Name: Gap Junction Protein Alpha 1
Chromosome: CHR6: 121756744 -121770873
Locus: 6q22.31
PLEKHG1 Gene Summary
The Pleckstrin Homology And RhoGEF Domain Containing G1 (PLEKHG1) gene is located on chr6 :150920998-151164799 at 6q25.1.
Gene Name: Pleckstrin Homology And RhoGEF Domain Containing G1
Chromosome: CHR6: 150920998 -151164799
Locus: 6q25.1
Gene Diseases
The PLEKHG1 GJA1 Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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