PLXNB2-P4HTM Fusion FISH Probe
The PLXNB2-P4HTM Fusion FISH Probe is used to confirm a fusion of the PLXNB2 and P4HTM genes. The fusion of the PLXNB2 and P4HTM genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLXNB2-P4HTM-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-RERE | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-REOR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-REGO | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-REGR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-REAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-ORRE | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-OROR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-ORGO | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GORE | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GOOR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GOGO | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GOGR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GRRE | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GROR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GRGO | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GRGR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-AQRE | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-AQOR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-AQGO | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-AQGR | 20 (40 μL) | 200 μL |
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| PLXNB2-P4HTM-20-AQAQ | 20 (40 μL) | 200 μL |
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PLXNB2 Gene Summary
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
Gene Name: Plexin B2
Chromosome: CHR22: 50713407 -50746001
Locus: 22q13.33
P4HTM Gene Summary
The product of this gene belongs to the family of prolyl 4-hydroxylases. This protein is a prolyl hydroxylase that may be involved in the degradation of hypoxia-inducible transcription factors under normoxia. It plays a role in adaptation to hypoxia and may be related to cellular oxygen sensing. Alternatively spliced variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Prolyl 4-hydroxylase, Transmembrane
Chromosome: CHR3: 49027340 -49044581
Locus: 3p21.3
Gene Diseases
The PLXNB2 P4HTM Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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