PLXNB2-ST3GAL1 Fusion FISH Probe
The PLXNB2-ST3GAL1 Fusion FISH Probe is used to confirm a fusion of the PLXNB2 and ST3GAL1 genes. The fusion of the PLXNB2 and ST3GAL1 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PLXNB2-ST3GAL1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-RERE | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-REOR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-REGO | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-REGR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-REAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-ORRE | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-OROR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-ORGO | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GORE | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GOOR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GOGO | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GOGR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GRRE | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GROR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GRGO | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GRGR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-AQRE | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-AQOR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-AQGO | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-AQGR | 20 (40 μL) | 200 μL |
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| PLXNB2-ST3GAL1-20-AQAQ | 20 (40 μL) | 200 μL |
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ST3GAL1 Gene Summary
The protein encoded by this gene is a type II membrane protein that catalyzes the transfer of sialic acid from CMP-sialic acid to galactose-containing substrates. The encoded protein is normally found in the Golgi but can be proteolytically processed to a soluble form. Correct glycosylation of the encoded protein may be critical to its sialyltransferase activity. This protein, which is a member of glycosyltransferase family 29, can use the same acceptor substrates as does sialyltransferase 4B. Two transcript variants encoding the same protein have been found for this gene. Other transcript variants may exist, but have not been fully characterized yet. [provided by RefSeq, Jul 2008]
Gene Name: ST3 Beta-galactoside Alpha-2,3-sialyltransferase 1
Chromosome: CHR8: 134467090 -134584183
Locus: 8q24.22
PLXNB2 Gene Summary
Members of the B class of plexins, such as PLXNB2 are transmembrane receptors that participate in axon guidance and cell migration in response to semaphorins (Perrot et al. (2002) [PubMed 12183458]).[supplied by OMIM, Mar 2008]
Gene Name: Plexin B2
Chromosome: CHR22: 50713407 -50746001
Locus: 22q13.33
Gene Diseases
The PLXNB2 ST3GAL1 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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