PMEPA1-PIGP Fusion FISH Probe
The PMEPA1-PIGP Fusion FISH Probe is used to confirm a fusion of the PMEPA1 and PIGP genes. The fusion of the PMEPA1 and PIGP genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PMEPA1-PIGP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-RERE | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-REOR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-REGO | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-REGR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-REAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-ORRE | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-OROR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-ORGO | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-ORAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GORE | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GOOR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GOGO | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GOGR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GOAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GRRE | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GROR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GRGO | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GRGR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-GRAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-AQRE | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-AQOR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-AQGO | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-AQGR | 20 (40 μL) | 200 μL |
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| PMEPA1-PIGP-20-AQAQ | 20 (40 μL) | 200 μL |
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PIGP Gene Summary
This gene encodes an enzyme involved in the first step of glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells that serves to anchor proteins to the cell surface. The encoded protein is a component of the GPI-N-acetylglucosaminyltransferase complex that catalyzes the transfer of N-acetylglucosamine (GlcNAc) from UDP-GlcNAc to phosphatidylinositol (PI). This gene is located in the Down Syndrome critical region on chromosome 21 and is a candidate for the pathogenesis of Down syndrome. This gene has multiple pseudogenes and is a member of the phosphatidylinositol glycan anchor biosynthesis gene family. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Feb 2016]
Gene Name: Phosphatidylinositol Glycan Anchor Biosynthesis Class P
Chromosome: CHR21: 38437663 -38445458
Locus: 21q22.13
PMEPA1 Gene Summary
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Prostate Transmembrane Protein, Androgen Induced 1
Chromosome: CHR20: 56223451 -56286541
Locus: 20q13.31
Gene Diseases
The PMEPA1 PIGP Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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