PMEPA1-RALY Fusion FISH Probe
The PMEPA1-RALY Fusion FISH Probe is used to confirm a fusion of the PMEPA1 and RALY genes. The fusion of the PMEPA1 and RALY genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PMEPA1-RALY-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-RERE | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-REOR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-REGO | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-REGR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-REAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-ORRE | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-OROR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-ORGO | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-ORAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GORE | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GOOR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GOGO | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GOGR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GOAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GRRE | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GROR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GRGO | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GRGR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-GRAQ | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-AQRE | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-AQOR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-AQGO | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-AQGR | 20 (40 μL) | 200 μL |
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| PMEPA1-RALY-20-AQAQ | 20 (40 μL) | 200 μL |
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RALY Gene Summary
This gene encodes a member of the heterogeneous nuclear ribonucleoprotein (hnRNP) gene family. This protein may play a role in pre-mRNA splicing and in embryonic development. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]
Gene Name: RALY Heterogeneous Nuclear Ribonucleoprotein
Chromosome: CHR20: 32581457 -32670991
Locus: 20q11.22
PMEPA1 Gene Summary
This gene encodes a transmembrane protein that contains a Smad interacting motif (SIM). Expression of this gene is induced by androgens and transforming growth factor beta, and the encoded protein suppresses the androgen receptor and transforming growth factor beta signaling pathways though interactions with Smad proteins. Overexpression of this gene may play a role in multiple types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
Gene Name: Prostate Transmembrane Protein, Androgen Induced 1
Chromosome: CHR20: 56223451 -56286541
Locus: 20q13.31
Gene Diseases
The PMEPA1 RALY Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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