POLA2-CAPN1 Fusion FISH Probe
The POLA2-CAPN1 Fusion FISH Probe is used to confirm a fusion of the POLA2 and CAPN1 genes. The fusion of the POLA2 and CAPN1 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLA2-CAPN1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-RERE | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-REOR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-REGO | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-REGR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-REAQ | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-ORRE | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-OROR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-ORGO | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-ORAQ | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GORE | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GOOR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GOGO | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GOGR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GOAQ | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GRRE | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GROR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GRGO | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GRGR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-GRAQ | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-AQRE | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-AQOR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-AQGO | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-AQGR | 20 (40 μL) | 200 μL |
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| POLA2-CAPN1-20-AQAQ | 20 (40 μL) | 200 μL |
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CAPN1 Gene Summary
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 1. Several transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2010]
Gene Name: Calpain 1
Chromosome: CHR11: 64948685 -64979477
Locus: 11q13.1
POLA2 Gene Summary
The DNA Polymerase Alpha 2, Accessory Subunit (POLA2) gene is located on chr11 :65029431-65065088 at 11q13.1.
Gene Name: DNA Polymerase Alpha 2, Accessory Subunit
Chromosome: CHR11: 65029431 -65065088
Locus: 11q13.1
Gene Diseases
The POLA2 CAPN1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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