POLH-C12ORF71 Fusion FISH Probe
The POLH-C12ORF71 Fusion FISH Probe is used to confirm a fusion of the POLH and C12ORF71 genes. The fusion of the POLH and C12ORF71 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLH-C12ORF71-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-RERE | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-REOR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-REGO | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-REGR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-REAQ | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-ORRE | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-OROR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-ORGO | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-ORAQ | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GORE | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GOOR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GOGO | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GOGR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GOAQ | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GRRE | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GROR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GRGO | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GRGR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-GRAQ | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-AQRE | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-AQOR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-AQGO | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-AQGR | 20 (40 μL) | 200 μL |
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| POLH-C12ORF71-20-AQAQ | 20 (40 μL) | 200 μL |
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POLH Gene Summary
This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2014]
Gene Name: DNA Polymerase Eta
Chromosome: CHR6: 43543877 -43588260
Locus: 6p21.1
C12orf71 Gene Summary
The Chromosome 12 Open Reading Frame 71 (C12orf71) gene is located on chr12 :27233989-27235455 at 12p11.23.
Gene Name: Chromosome 12 Open Reading Frame 71
Chromosome: CHR12: 27233989 -27235455
Locus: 12p11.23
Gene Diseases
The POLH C12ORF71 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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