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POLK-SKIV2L2 Fusion FISH Probe

The POLK-SKIV2L2 Fusion FISH Probe is used to confirm a fusion of the POLK and SKIV2L2 genes. The fusion of the POLK and SKIV2L2 genes has been associated with Rectum Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
POLK-SKIV2L2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
POLK-SKIV2L2-20-RERE 20 (40 μL) 200 μL
POLK-SKIV2L2-20-REOR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-REGO 20 (40 μL) 200 μL
POLK-SKIV2L2-20-REGR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-REAQ 20 (40 μL) 200 μL
POLK-SKIV2L2-20-ORRE 20 (40 μL) 200 μL
POLK-SKIV2L2-20-OROR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-ORGO 20 (40 μL) 200 μL
POLK-SKIV2L2-20-ORAQ 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GORE 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GOOR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GOGO 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GOGR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GOAQ 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GRRE 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GROR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GRGO 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GRGR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-GRAQ 20 (40 μL) 200 μL
POLK-SKIV2L2-20-AQRE 20 (40 μL) 200 μL
POLK-SKIV2L2-20-AQOR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-AQGO 20 (40 μL) 200 μL
POLK-SKIV2L2-20-AQGR 20 (40 μL) 200 μL
POLK-SKIV2L2-20-AQAQ 20 (40 μL) 200 μL

SKIV2L2 Gene Summary

The Ski2 Like RNA Helicase 2 (SKIV2L2) gene is located on chr5 :54603575-54721409 at 5q11.2.

Gene Name: Ski2 Like RNA Helicase 2

Chromosome: CHR5: 54603575 -54721409

Locus: 5q11.2

POLK Gene Summary

This gene encodes a member of the DNA polymerase type-Y family of proteins. The encoded protein is a specialized DNA polymerase that catalyzes translesion DNA synthesis, which allows DNA replication in the presence of DNA lesions. Human cell lines lacking a functional copy of this gene exhibit impaired genome integrity and enhanced susceptibility to oxidative damage. Mutations in this gene that impair enzyme activity may be associated with prostate cancer in human patients. [provided by RefSeq, Sep 2016]

Gene Name: DNA Polymerase Kappa

Chromosome: CHR5: 74807656 -74895646

Locus: 5q13.3

Gene Diseases

The POLK SKIV2L2 Fusion has been associated with the following diseases:

Disease Name
Rectum Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.