POLR1A-REEP1 Fusion FISH Probe
The POLR1A-REEP1 Fusion FISH Probe is used to confirm a fusion of the POLR1A and REEP1 genes. The fusion of the POLR1A and REEP1 genes has been associated with Lung Adenocarcinoma, Lung Squamous Cell Carcinoma, Kidney Renal Clear Cell Carcinoma, Kidney Renal Clear Cell Carcinoma, and Kidney Chromophobe. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLR1A-REEP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-RERE | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-REOR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-REGO | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-REGR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-REAQ | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-ORRE | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-OROR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-ORGO | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GORE | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GOOR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GOGO | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GOGR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GRRE | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GROR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GRGO | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GRGR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-AQRE | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-AQOR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-AQGO | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-AQGR | 20 (40 μL) | 200 μL |
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| POLR1A-REEP1-20-AQAQ | 20 (40 μL) | 200 μL |
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POLR1A Gene Summary
The protein encoded by this gene is the largest subunit of the RNA polymerase I complex. The encoded protein represents the catalytic subunit of the complex, which transcribes DNA into ribosomal RNA precursors. Defects in this gene are a cause of the Cincinnati type of acrofacial dysostosis. [provided by RefSeq, May 2016]
Gene Name: RNA Polymerase I Subunit A
Chromosome: CHR2: 86253450 -86333278
Locus: 2p11.2
REEP1 Gene Summary
This gene encodes a mitochondrial protein that functions to enhance the cell surface expression of odorant receptors. Mutations in this gene cause spastic paraplegia autosomal dominant type 31, a neurodegenerative disorder. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2009]
Gene Name: Receptor Accessory Protein 1
Chromosome: CHR2: 86441119 -86565206
Locus: 2p11.2
Gene Diseases
The POLR1A REEP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
| Lung Squamous Cell Carcinoma |
| Kidney Renal Clear Cell Carcinoma |
| Kidney Renal Clear Cell Carcinoma |
| Kidney Chromophobe |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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