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POLR3B-RBM19 Fusion FISH Probe

The POLR3B-RBM19 Fusion FISH Probe is used to confirm a fusion of the POLR3B and RBM19 genes. The fusion of the POLR3B and RBM19 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
POLR3B-RBM19-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
POLR3B-RBM19-20-RERE 20 (40 μL) 200 μL
POLR3B-RBM19-20-REOR 20 (40 μL) 200 μL
POLR3B-RBM19-20-REGO 20 (40 μL) 200 μL
POLR3B-RBM19-20-REGR 20 (40 μL) 200 μL
POLR3B-RBM19-20-REAQ 20 (40 μL) 200 μL
POLR3B-RBM19-20-ORRE 20 (40 μL) 200 μL
POLR3B-RBM19-20-OROR 20 (40 μL) 200 μL
POLR3B-RBM19-20-ORGO 20 (40 μL) 200 μL
POLR3B-RBM19-20-ORAQ 20 (40 μL) 200 μL
POLR3B-RBM19-20-GORE 20 (40 μL) 200 μL
POLR3B-RBM19-20-GOOR 20 (40 μL) 200 μL
POLR3B-RBM19-20-GOGO 20 (40 μL) 200 μL
POLR3B-RBM19-20-GOGR 20 (40 μL) 200 μL
POLR3B-RBM19-20-GOAQ 20 (40 μL) 200 μL
POLR3B-RBM19-20-GRRE 20 (40 μL) 200 μL
POLR3B-RBM19-20-GROR 20 (40 μL) 200 μL
POLR3B-RBM19-20-GRGO 20 (40 μL) 200 μL
POLR3B-RBM19-20-GRGR 20 (40 μL) 200 μL
POLR3B-RBM19-20-GRAQ 20 (40 μL) 200 μL
POLR3B-RBM19-20-AQRE 20 (40 μL) 200 μL
POLR3B-RBM19-20-AQOR 20 (40 μL) 200 μL
POLR3B-RBM19-20-AQGO 20 (40 μL) 200 μL
POLR3B-RBM19-20-AQGR 20 (40 μL) 200 μL
POLR3B-RBM19-20-AQAQ 20 (40 μL) 200 μL

RBM19 Gene Summary

This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq, Apr 2009]

Gene Name: RNA Binding Motif Protein 19

Chromosome: CHR12: 114254542 -114404176

Locus: 12q24.13-q24.21

POLR3B Gene Summary

This gene encodes the second largest subunit of RNA polymerase III, the polymerase responsible for synthesizing transfer and small ribosomal RNAs in eukaryotes. The largest subunit and the encoded protein form the catalytic center of RNA polymerase III. Mutations in this gene are a cause of hypomyelinating leukodystrophy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]

Gene Name: RNA Polymerase III Subunit B

Chromosome: CHR12: 106751435 -106903976

Locus: 12q23.3

Gene Diseases

The POLR3B RBM19 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.