POLR3H-CTNND2 Fusion FISH Probe
The POLR3H-CTNND2 Fusion FISH Probe is used to confirm a fusion of the POLR3H and CTNND2 genes. The fusion of the POLR3H and CTNND2 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POLR3H-CTNND2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-RERE | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-REOR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-REGO | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-REGR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-REAQ | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-ORRE | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-OROR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-ORGO | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-ORAQ | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GORE | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GOOR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GOGO | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GOGR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GOAQ | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GRRE | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GROR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GRGO | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GRGR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-GRAQ | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-AQRE | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-AQOR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-AQGO | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-AQGR | 20 (40 μL) | 200 μL |
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| POLR3H-CTNND2-20-AQAQ | 20 (40 μL) | 200 μL |
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CTNND2 Gene Summary
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2013]
Gene Name: Catenin Delta 2
Chromosome: CHR5: 10971951 -11904110
Locus: 5p15.2
POLR3H Gene Summary
The RNA Polymerase III Subunit H (POLR3H) gene is located on chr22 :41921802-41940479 at 22q13.2.
Gene Name: RNA Polymerase III Subunit H
Chromosome: CHR22: 41921802 -41940479
Locus: 22q13.2
Gene Diseases
The POLR3H CTNND2 Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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