POR-PIBF1 Fusion FISH Probe
The POR-PIBF1 Fusion FISH Probe is used to confirm a fusion of the POR and PIBF1 genes. The fusion of the POR and PIBF1 genes has been associated with Thyroid Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| POR-PIBF1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-RERE | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-REOR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-REGO | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-REGR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-REAQ | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-ORRE | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-OROR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-ORGO | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-ORAQ | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GORE | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GOOR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GOGO | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GOGR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GOAQ | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GRRE | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GROR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GRGO | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GRGR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-GRAQ | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-AQRE | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-AQOR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-AQGO | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-AQGR | 20 (40 μL) | 200 μL |
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| POR-PIBF1-20-AQAQ | 20 (40 μL) | 200 μL |
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POR Gene Summary
This gene encodes an endoplasmic reticulum membrane oxidoreductase with an FAD-binding domain and a flavodoxin-like domain. The protein binds two cofactors, FAD and FMN, which allow it to donate electrons directly from NADPH to all microsomal P450 enzymes. Mutations in this gene have been associated with various diseases, including apparent combined P450C17 and P450C21 deficiency, amenorrhea and disordered steroidogenesis, congenital adrenal hyperplasia and Antley-Bixler syndrome. [provided by RefSeq, Jul 2008]
Gene Name: Cytochrome P450 Oxidoreductase
Chromosome: CHR7: 75544419 -75616173
Locus: 7q11.23
PIBF1 Gene Summary
This gene encodes a protein that is induced by the steroid hormone progesterone and plays a role in the maintenance of pregnancy. The encoded protein regulates multiple facets of the immune system to promote normal pregnancy including cytokine synthesis, natural killer (NK) cell activity, and arachidonic acid metabolism. Low serum levels of this protein have been associated with spontaneous pre-term labor in humans. This protein may promote the proliferation, migration and invasion of glioma. [provided by RefSeq, Mar 2017]
Gene Name: Progesterone Immunomodulatory Binding Factor 1
Chromosome: CHR13: 73356229 -73590591
Locus: 13q21.33-q22.1
Gene Diseases
The POR PIBF1 Fusion has been associated with the following diseases:
| Disease Name |
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| Thyroid Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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