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PPARA-BCL2L13 Fusion FISH Probe

The PPARA-BCL2L13 Fusion FISH Probe is used to confirm a fusion of the PPARA and BCL2L13 genes. The fusion of the PPARA and BCL2L13 genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PPARA-BCL2L13-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PPARA-BCL2L13-20-RERE 20 (40 μL) 200 μL
PPARA-BCL2L13-20-REOR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-REGO 20 (40 μL) 200 μL
PPARA-BCL2L13-20-REGR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-REAQ 20 (40 μL) 200 μL
PPARA-BCL2L13-20-ORRE 20 (40 μL) 200 μL
PPARA-BCL2L13-20-OROR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-ORGO 20 (40 μL) 200 μL
PPARA-BCL2L13-20-ORAQ 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GORE 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GOOR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GOGO 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GOGR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GOAQ 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GRRE 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GROR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GRGO 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GRGR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-GRAQ 20 (40 μL) 200 μL
PPARA-BCL2L13-20-AQRE 20 (40 μL) 200 μL
PPARA-BCL2L13-20-AQOR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-AQGO 20 (40 μL) 200 μL
PPARA-BCL2L13-20-AQGR 20 (40 μL) 200 μL
PPARA-BCL2L13-20-AQAQ 20 (40 μL) 200 μL

PPARA Gene Summary

Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers; this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals that contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor. Multiple alternatively spliced transcript variants have been described for this gene, although the full-length nature of only two has been determined. [provided by RefSeq, Jul 2008]

Gene Name: Peroxisome Proliferator Activated Receptor Alpha

Chromosome: CHR22: 46546498 -46639653

Locus: 22q13.31

BCL2L13 Gene Summary

This gene encodes a mitochondrially-localized protein with conserved B-cell lymphoma 2 homology motifs. Overexpression of the encoded protein results in apoptosis. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Jul 2012]

Gene Name: BCL2 Like 13

Chromosome: CHR22: 18121484 -18211989

Locus: 22q11.21

Gene Diseases

The PPARA BCL2L13 Fusion has been associated with the following diseases:

Disease Name
Skin Cutaneous Melanoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.