PPCDC-LMAN1L Fusion FISH Probe
The PPCDC-LMAN1L Fusion FISH Probe is used to confirm a fusion of the PPCDC and LMAN1L genes. The fusion of the PPCDC and LMAN1L genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPCDC-LMAN1L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-RERE | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-REOR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-REGO | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-REGR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-REAQ | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-ORRE | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-OROR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-ORGO | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GORE | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GOOR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GOGO | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GOGR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GRRE | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GROR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GRGO | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GRGR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-AQRE | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-AQOR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-AQGO | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-AQGR | 20 (40 μL) | 200 μL |
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| PPCDC-LMAN1L-20-AQAQ | 20 (40 μL) | 200 μL |
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PPCDC Gene Summary
Biosynthesis of coenzyme A (CoA) from pantothenic acid (vitamin B5) is an essential universal pathway in prokaryotes and eukaryotes. PPCDC (EC 4.1.1.36), one of the last enzymes in this pathway, converts phosphopantothenoylcysteine to 4-prime-phosphopantetheine (Daugherty et al., 2002 [PubMed 11923312]).[supplied by OMIM, Mar 2008]
Gene Name: Phosphopantothenoylcysteine Decarboxylase
Chromosome: CHR15: 75315926 -75343067
Locus: 15q24.2
LMAN1L Gene Summary
This gene encodes a mannose-binding type 1 transmembrane protein that contains an N-terminal lectin-like carbohydrate recognition domain. The encoded protein is similar in structure to lectins found in leguminous plants. This lectin is thought to transport newly synthesized glycoproteins from the endoplasmic reticulum (ER) to the ER-Golgi intermediate compartment. [provided by RefSeq, Jan 2017]
Gene Name: Lectin, Mannose Binding 1 Like
Chromosome: CHR15: 75105193 -75118099
Locus: 15q24.1
Gene Diseases
The PPCDC LMAN1L Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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