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PPFIA2-TRHDE Fusion FISH Probe

The PPFIA2-TRHDE Fusion FISH Probe is used to confirm a fusion of the PPFIA2 and TRHDE genes. The fusion of the PPFIA2 and TRHDE genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PPFIA2-TRHDE-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-RERE 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-REOR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-REGO 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-REGR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-REAQ 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-ORRE 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-OROR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-ORGO 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-ORAQ 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GORE 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GOOR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GOGO 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GOGR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GOAQ 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GRRE 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GROR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GRGO 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GRGR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-GRAQ 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-AQRE 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-AQOR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-AQGO 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-AQGR 20 (40 μL) 200 μL
PPFIA2-TRHDE-20-AQAQ 20 (40 μL) 200 μL

PPFIA2 Gene Summary

The protein encoded by this gene is a member of the LAR protein-tyrosine phosphatase-interacting protein (liprin) family. Liprins interact with members of LAR family of transmembrane protein tyrosine phosphatases, which are known to be important for axon guidance and mammary gland development. It has been proposed that liprins are multivalent proteins that form complex structures and act as scaffolds for the recruitment and anchoring of LAR family of tyrosine phosphatases. This protein has been shown to bind the calcium/calmodulin-dependent serine protein kinase (MAGUK family) protein (also known as CASK) and proposed to regulate higher-order brain functions in mammals. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]

Gene Name: PTPRF Interacting Protein Alpha 2

Chromosome: CHR12: 81652044 -82153109

Locus: 12q21.31

TRHDE Gene Summary

This gene encodes a member of the peptidase M1 family. The encoded protein is an extracellular peptidase that specifically cleaves and inactivates the neuropeptide thyrotropin-releasing hormone.[provided by RefSeq, Dec 2008]

Gene Name: Thyrotropin Releasing Hormone Degrading Enzyme

Chromosome: CHR12: 72666528 -73059422

Locus: 12q21.1

Gene Diseases

The PPFIA2 TRHDE Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.