PPP1R12C-CLEC11A Fusion FISH Probe
The PPP1R12C-CLEC11A Fusion FISH Probe is used to confirm a fusion of the PPP1R12C and CLEC11A genes. The fusion of the PPP1R12C and CLEC11A genes has been associated with Uterine Carcinosarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP1R12C-CLEC11A-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-RERE | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-REOR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-REGO | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-REGR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-OROR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GORE | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GROR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP1R12C-CLEC11A-20-AQAQ | 20 (40 μL) | 200 μL |
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CLEC11A Gene Summary
This gene encodes a member of the C-type lectin superfamily. The encoded protein is a secreted sulfated glycoprotein and functions as a growth factor for primitive hematopoietic progenitor cells. An alternative splice variant has been described but its biological nature has not been determined. [provided by RefSeq, Jul 2008]
Gene Name: C-type Lectin Domain Containing 11A
Chromosome: CHR19: 51226604 -51228981
Locus: 19q13.33
PPP1R12C Gene Summary
The gene encodes a subunit of myosin phosphatase. The encoded protein regulates the catalytic activity of protein phosphatase 1 delta and assembly of the actin cytoskeleton. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Oct 2012]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 12C
Chromosome: CHR19: 55602280 -55628927
Locus: 19q13.42
Gene Diseases
The PPP1R12C CLEC11A Fusion has been associated with the following diseases:
| Disease Name |
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| Uterine Carcinosarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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