PPP1R15A-EMP3 Fusion FISH Probe
The PPP1R15A-EMP3 Fusion FISH Probe is used to confirm a fusion of the PPP1R15A and EMP3 genes. The fusion of the PPP1R15A and EMP3 genes has been associated with Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP1R15A-EMP3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-RERE | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-REOR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-REGO | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-REGR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-OROR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GORE | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GROR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP1R15A-EMP3-20-AQAQ | 20 (40 μL) | 200 μL |
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EMP3 Gene Summary
The protein encoded by this gene belongs to the PMP-22/EMP/MP20 family of proteins. The protein contains four transmembrane domains and two N-linked glycosylation sites. It is thought to be involved in cell proliferation, cell-cell interactions and function as a tumor suppressor. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Gene Name: Epithelial Membrane Protein 3
Chromosome: CHR19: 48828628 -48833810
Locus: 19q13.33
PPP1R15A Gene Summary
This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 1 Regulatory Subunit 15A
Chromosome: CHR19: 49375648 -49379319
Locus: 19q13.33
Gene Diseases
The PPP1R15A EMP3 Fusion has been associated with the following diseases:
| Disease Name |
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| Cervical Squamous Cell Carcinoma And Endocervical Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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