PPP2R2C-CTBP1 Fusion FISH Probe
The PPP2R2C-CTBP1 Fusion FISH Probe is used to confirm a fusion of the PPP2R2C and CTBP1 genes. The fusion of the PPP2R2C and CTBP1 genes has been associated with Brain Lower Grade Glioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2R2C-CTBP1-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2R2C-CTBP1-20-AQAQ | 20 (40 μL) | 200 μL |
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CTBP1 Gene Summary
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants. [provided by RefSeq, Jul 2008]
Gene Name: C-terminal Binding Protein 1
Chromosome: CHR4: 1205227 -1242908
Locus: 4p16.3
PPP2R2C Gene Summary
The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Regulatory Subunit Bgamma
Chromosome: CHR4: 6322304 -6565327
Locus: 4p16.1
Gene Diseases
The PPP2R2C CTBP1 Fusion has been associated with the following diseases:
| Disease Name |
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| Brain Lower Grade Glioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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