PPP2R5D-ASCC3 Fusion FISH Probe
The PPP2R5D-ASCC3 Fusion FISH Probe is used to confirm a fusion of the PPP2R5D and ASCC3 genes. The fusion of the PPP2R5D and ASCC3 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP2R5D-ASCC3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-RERE | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-REOR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-REGO | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-REGR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-OROR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GORE | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GROR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP2R5D-ASCC3-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP2R5D Gene Summary
The product of this gene belongs to the phosphatase 2A regulatory subunit B family. Protein phosphatase 2A is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a delta isoform of the regulatory subunit B56 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Protein Phosphatase 2 Regulatory Subunit B'delta
Chromosome: CHR6: 42952329 -42980080
Locus: 6p21.1
ASCC3 Gene Summary
This gene encodes a protein that belongs to a family of helicases that are involved in the ATP-dependent unwinding of nucleic acid duplexes. The encoded protein is the largest subunit of the activating signal cointegrator 1 complex that is involved in DNA repair and resistance to alkylation damage. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Activating Signal Cointegrator 1 Complex Subunit 3
Chromosome: CHR6: 100956607 -101329224
Locus: 6q16.3
Gene Diseases
The PPP2R5D ASCC3 Fusion has been associated with the following diseases:
| Disease Name |
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| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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