PPP3CC-PIWIL2 Fusion FISH Probe
The PPP3CC-PIWIL2 Fusion FISH Probe is used to confirm a fusion of the PPP3CC and PIWIL2 genes. The fusion of the PPP3CC and PIWIL2 genes has been associated with Stomach Adenocarcinoma, Head And Neck Squamous Cell Carcinoma , and Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PPP3CC-PIWIL2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-RERE | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-REOR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-REGO | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-REGR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-REAQ | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-ORRE | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-OROR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-ORGO | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GORE | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GOOR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GOGO | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GOGR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GRRE | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GROR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GRGO | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GRGR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-AQRE | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-AQOR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-AQGO | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-AQGR | 20 (40 μL) | 200 μL |
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| PPP3CC-PIWIL2-20-AQAQ | 20 (40 μL) | 200 μL |
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PPP3CC Gene Summary
Calcineurin is a calcium-dependent, calmodulin-stimulated protein phosphatase involved in the downstream regulation of dopaminergic signal transduction. Calcineurin is composed of a regulatory subunit and a catalytic subunit. The protein encoded by this gene represents one of the regulatory subunits that has been found for calcineurin. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Protein Phosphatase 3 Catalytic Subunit Gamma
Chromosome: CHR8: 22298482 -22398657
Locus: 8p21.3
PIWIL2 Gene Summary
PIWIL2 belongs to the Argonaute family of proteins, which function in development and maintenance of germline stem cells (Sasaki et al., 2003 [PubMed 12906857]).[supplied by OMIM, Mar 2008]
Gene Name: Piwi Like RNA-mediated Gene Silencing 2
Chromosome: CHR8: 22132809 -22213584
Locus: 8p21.3
Gene Diseases
The PPP3CC PIWIL2 Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
| Head And Neck Squamous Cell Carcinoma |
| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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