PRAME-HDLBP Fusion FISH Probe
The PRAME-HDLBP Fusion FISH Probe is used to confirm a fusion of the PRAME and HDLBP genes. The fusion of the PRAME and HDLBP genes has been associated with Skin Cutaneous Melanoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRAME-HDLBP-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-RERE | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-REOR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-REGO | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-REGR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-REAQ | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-ORRE | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-OROR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-ORGO | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GORE | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GOOR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GOGO | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GOGR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GRRE | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GROR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GRGO | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GRGR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-AQRE | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-AQOR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-AQGO | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-AQGR | 20 (40 μL) | 200 μL |
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| PRAME-HDLBP-20-AQAQ | 20 (40 μL) | 200 μL |
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HDLBP Gene Summary
The protein encoded by this gene binds high density lipoprotein (HDL) and may function to regulate excess cholesterol levels in cells. The encoded protein also binds RNA and can induce heterochromatin formation. [provided by RefSeq, Mar 2016]
Gene Name: High Density Lipoprotein Binding Protein
Chromosome: CHR2: 242166681 -242255115
Locus: 2q37.3
PRAME Gene Summary
This gene encodes an antigen that is preferentially expressed in human melanomas and that is recognized by cytolytic T lymphocytes. It is not expressed in normal tissues, except testis. The encoded protein acts as a repressor of retinoic acid receptor, and likely confers a growth advantage to cancer cells via this function. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2014]
Gene Name: Preferentially Expressed Antigen In Melanoma
Chromosome: CHR22: 22890122 -22901696
Locus: 22q11.22
Gene Diseases
The PRAME HDLBP Fusion has been associated with the following diseases:
| Disease Name |
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| Skin Cutaneous Melanoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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