PRKAG2-WASL Fusion FISH Probe
The PRKAG2-WASL Fusion FISH Probe is used to confirm a fusion of the PRKAG2 and WASL genes. The fusion of the PRKAG2 and WASL genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKAG2-WASL-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-RERE | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-REOR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-REGO | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-REGR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-OROR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GORE | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GROR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKAG2-WASL-20-AQAQ | 20 (40 μL) | 200 μL |
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WASL Gene Summary
This gene encodes a member of the Wiskott-Aldrich syndrome (WAS) protein family. Wiskott-Aldrich syndrome proteins share similar domain structure, and associate with a variety of signaling molecules to alter the actin cytoskeleton. The encoded protein is highly expressed in neural tissues, and interacts with several proteins involved in cytoskeletal organization, including cell division control protein 42 (CDC42) and the actin-related protein-2/3 (ARP2/3) complex. The encoded protein may be involved in the formation of long actin microspikes, and in neurite extension. [provided by RefSeq, Jul 2013]
Gene Name: Wiskott-Aldrich Syndrome Like
Chromosome: CHR7: 123321996 -123389116
Locus: 7q31.32
PRKAG2 Gene Summary
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jan 2015]
Gene Name: Protein Kinase AMP-activated Non-catalytic Subunit Gamma 2
Chromosome: CHR7: 151253200 -151574316
Locus: 7q36.1
Gene Diseases
The PRKAG2 WASL Fusion has been associated with the following diseases:
| Disease Name |
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| Mesothelioma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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