PRKD3-TMEM51 Fusion FISH Probe
The PRKD3-TMEM51 Fusion FISH Probe is used to confirm a fusion of the PRKD3 and TMEM51 genes. The fusion of the PRKD3 and TMEM51 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRKD3-TMEM51-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-RERE | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-REOR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-REGO | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-REGR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-REAQ | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-ORRE | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-OROR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-ORGO | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GORE | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GOOR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GOGO | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GOGR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GRRE | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GROR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GRGO | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GRGR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-AQRE | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-AQOR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-AQGO | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-AQGR | 20 (40 μL) | 200 μL |
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| PRKD3-TMEM51-20-AQAQ | 20 (40 μL) | 200 μL |
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PRKD3 Gene Summary
This gene belongs to the multigene protein kinase D family of serine/threonine kinases, which bind diacylglycerol and phorbol esters. Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain. The C-terminal region contains the catalytic domain and is distantly related to calcium-regulated kinases. Catalytic activity of this enzyme promotes its nuclear localization. This protein has been implicated in a variety of functions including negative regulation of human airway epithelial barrier formation, growth regulation of breast and prostate cancer cells, and vesicle trafficking. [provided by RefSeq, Jan 2015]
Gene Name: Protein Kinase D3
Chromosome: CHR2: 37477645 -37544222
Locus: 2p22.2
TMEM51 Gene Summary
The Transmembrane Protein 51 (TMEM51) gene is located on chr1 :15479027-15546974 at 1p36.21.
Gene Name: Transmembrane Protein 51
Chromosome: CHR1: 15479027 -15546974
Locus: 1p36.21
Gene Diseases
The PRKD3 TMEM51 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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