PRMT7-EXOC4 Fusion FISH Probe
The PRMT7-EXOC4 Fusion FISH Probe is used to confirm a fusion of the PRMT7 and EXOC4 genes. The fusion of the PRMT7 and EXOC4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRMT7-EXOC4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-RERE | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-REOR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-REGO | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-REGR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-REAQ | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-ORRE | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-OROR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-ORGO | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GORE | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GOOR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GOGO | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GOGR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GRRE | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GROR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GRGO | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GRGR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-AQRE | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-AQOR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-AQGO | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-AQGR | 20 (40 μL) | 200 μL |
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| PRMT7-EXOC4-20-AQAQ | 20 (40 μL) | 200 μL |
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PRMT7 Gene Summary
This gene encodes a member of the protein arginine N-methyltransferase family of proteins. The encoded enzyme transfers single methyl groups to arginine residues to generate monomethylarginines on histone proteins as well as other protein substrates. This enzyme plays a role in a wide range of biological processes, including neuronal differentiation, male germ line imprinting, small nuclear ribonucleoprotein biogenesis, and regulation of the Wnt signaling pathway. Mutations in this gene underlie multiple related syndromes in human patients characterized by intellectual disability, short stature and other features. The encoded protein may promote breast cancer cell invasion and metastasis in human patients. [provided by RefSeq, May 2017]
Gene Name: Protein Arginine Methyltransferase 7
Chromosome: CHR16: 68344876 -68391169
Locus: 16q22.1
EXOC4 Gene Summary
The protein encoded by this gene is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Gene Name: Exocyst Complex Component 4
Chromosome: CHR7: 132937822 -133750513
Locus: 7q33
Gene Diseases
The PRMT7 EXOC4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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