PRPF3-CTSS Fusion FISH Probe
The PRPF3-CTSS Fusion FISH Probe is used to confirm a fusion of the PRPF3 and CTSS genes. The fusion of the PRPF3 and CTSS genes has been associated with Lung Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF3-CTSS-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF3-CTSS-20-AQAQ | 20 (40 μL) | 200 μL |
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CTSS Gene Summary
The protein encoded by this gene, a member of the peptidase C1 family, is a lysosomal cysteine proteinase that may participate in the degradation of antigenic proteins to peptides for presentation on MHC class II molecules. The encoded protein can function as an elastase over a broad pH range in alveolar macrophages. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Dec 2010]
Gene Name: Cathepsin S
Chromosome: CHR1: 150702671 -150738433
Locus: 1q21.3
PRPF3 Gene Summary
The removal of introns from nuclear pre-mRNAs occurs on complexes called spliceosomes, which are made up of 4 small nuclear ribonucleoprotein (snRNP) particles and an undefined number of transiently associated splicing factors. This gene product is one of several proteins that associate with U4 and U6 snRNPs. Mutations in this gene are associated with retinitis pigmentosa-18. [provided by RefSeq, Jul 2008]
Gene Name: Pre-mRNA Processing Factor 3
Chromosome: CHR1: 150293927 -150325704
Locus: 1q21.2
Gene Diseases
The PRPF3 CTSS Fusion has been associated with the following diseases:
| Disease Name |
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| Lung Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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