PRPF40B-CDH4 Fusion FISH Probe
The PRPF40B-CDH4 Fusion FISH Probe is used to confirm a fusion of the PRPF40B and CDH4 genes. The fusion of the PRPF40B and CDH4 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRPF40B-CDH4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-RERE | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-REOR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-REGO | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-REGR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-REAQ | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-ORRE | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-OROR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-ORGO | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GORE | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GOOR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GOGO | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GOGR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GRRE | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GROR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GRGO | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GRGR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-AQRE | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-AQOR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-AQGO | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-AQGR | 20 (40 μL) | 200 μL |
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| PRPF40B-CDH4-20-AQAQ | 20 (40 μL) | 200 μL |
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CDH4 Gene Summary
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Gene Name: Cadherin 4
Chromosome: CHR20: 59827558 -60512299
Locus: 20q13.33
PRPF40B Gene Summary
This gene encodes a WW-domain containing protein similar to yeast splicing factor PRP40. This protein has been shown to interact with Huntingtin and methyl CpG binding protein 2 (MeCP2). Alternative splicing results in different transcript variants. [provided by RefSeq, Aug 2014]
Gene Name: Pre-mRNA Processing Factor 40 Homolog B
Chromosome: CHR12: 50017402 -50038449
Locus: 12q13.12
Gene Diseases
The PRPF40B CDH4 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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