PRRC2B-UHRF2 Fusion FISH Probe
The PRRC2B-UHRF2 Fusion FISH Probe is used to confirm a fusion of the PRRC2B and UHRF2 genes. The fusion of the PRRC2B and UHRF2 genes has been associated with Head And Neck Squamous Cell Carcinoma . These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PRRC2B-UHRF2-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-RERE | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-REOR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-REGO | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-REGR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-REAQ | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-ORRE | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-OROR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-ORGO | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-ORAQ | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GORE | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GOOR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GOGO | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GOGR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GOAQ | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GRRE | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GROR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GRGO | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GRGR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-GRAQ | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-AQRE | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-AQOR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-AQGO | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-AQGR | 20 (40 μL) | 200 μL |
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| PRRC2B-UHRF2-20-AQAQ | 20 (40 μL) | 200 μL |
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PRRC2B Gene Summary
The Proline Rich Coiled-coil 2B (PRRC2B) gene is located on chr9 :134305476-134375575 at 9q34.13.
Gene Name: Proline Rich Coiled-coil 2B
Chromosome: CHR9: 134305476 -134375575
Locus: 9q34.13
UHRF2 Gene Summary
This gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding. [provided by RefSeq, Feb 2012]
Gene Name: Ubiquitin Like With PHD And Ring Finger Domains 2
Chromosome: CHR9: 6413150 -6507051
Locus: 9p24.1
Gene Diseases
The PRRC2B UHRF2 Fusion has been associated with the following diseases:
| Disease Name |
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| Head And Neck Squamous Cell Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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