PSMA3-ACTR10 Fusion FISH Probe
The PSMA3-ACTR10 Fusion FISH Probe is used to confirm a fusion of the PSMA3 and ACTR10 genes. The fusion of the PSMA3 and ACTR10 genes has been associated with Liver Hepatocellular Carcinoma, Pancreatic Adenocarcinoma, and Esophageal Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PSMA3-ACTR10-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-RERE | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-REOR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-REGO | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-REGR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-REAQ | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-ORRE | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-OROR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-ORGO | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-ORAQ | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GORE | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GOOR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GOGO | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GOGR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GOAQ | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GRRE | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GROR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GRGO | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GRGR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-GRAQ | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-AQRE | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-AQOR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-AQGO | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-AQGR | 20 (40 μL) | 200 μL |
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| PSMA3-ACTR10-20-AQAQ | 20 (40 μL) | 200 μL |
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PSMA3 Gene Summary
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Two alternative transcripts encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]
Gene Name: Proteasome Subunit Alpha 3
Chromosome: CHR14: 58711522 -58738727
Locus: 14q23.1
ACTR10 Gene Summary
The Actin Related Protein 10 Homolog (ACTR10) gene is located on chr14 :58666832-58702353 at 14q23.1.
Gene Name: Actin Related Protein 10 Homolog
Chromosome: CHR14: 58666832 -58702353
Locus: 14q23.1
Gene Diseases
The PSMA3 ACTR10 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
| Pancreatic Adenocarcinoma |
| Esophageal Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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