PTPRN2-IMMP2L Fusion FISH Probe
The PTPRN2-IMMP2L Fusion FISH Probe is used to confirm a fusion of the PTPRN2 and IMMP2L genes. The fusion of the PTPRN2 and IMMP2L genes has been associated with Stomach Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRN2-IMMP2L-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRN2-IMMP2L-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRN2 Gene Summary
This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type N2
Chromosome: CHR7: 157331749 -158380482
Locus: 7q36.3
IMMP2L Gene Summary
This gene encodes a protein involved in processing the signal peptide sequences used to direct mitochondrial proteins to the mitochondria. The encoded protein resides in the mitochondria and is one of the necessary proteins for the catalytic activity of the mitochondrial inner membrane peptidase (IMP) complex. Two variants that encode the same protein have been described for this gene. [provided by RefSeq, Sep 2011]
Gene Name: Inner Mitochondrial Membrane Peptidase Subunit 2
Chromosome: CHR7: 110303109 -111202347
Locus: 7q31.1
Gene Diseases
The PTPRN2 IMMP2L Fusion has been associated with the following diseases:
| Disease Name |
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| Stomach Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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