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PTPRR-KCNC2 Fusion FISH Probe

The PTPRR-KCNC2 Fusion FISH Probe is used to confirm a fusion of the PTPRR and KCNC2 genes. The fusion of the PTPRR and KCNC2 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PTPRR-KCNC2-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PTPRR-KCNC2-20-RERE 20 (40 μL) 200 μL
PTPRR-KCNC2-20-REOR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-REGO 20 (40 μL) 200 μL
PTPRR-KCNC2-20-REGR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-REAQ 20 (40 μL) 200 μL
PTPRR-KCNC2-20-ORRE 20 (40 μL) 200 μL
PTPRR-KCNC2-20-OROR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-ORGO 20 (40 μL) 200 μL
PTPRR-KCNC2-20-ORAQ 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GORE 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GOOR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GOGO 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GOGR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GOAQ 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GRRE 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GROR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GRGO 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GRGR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-GRAQ 20 (40 μL) 200 μL
PTPRR-KCNC2-20-AQRE 20 (40 μL) 200 μL
PTPRR-KCNC2-20-AQOR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-AQGO 20 (40 μL) 200 μL
PTPRR-KCNC2-20-AQGR 20 (40 μL) 200 μL
PTPRR-KCNC2-20-AQAQ 20 (40 μL) 200 μL

KCNC2 Gene Summary

The Shaker gene family of Drosophila encodes components of voltage-gated potassium channels and is comprised of four subfamilies. Based on sequence similarity, this gene is similar to one of these subfamilies, namely the Shaw subfamily. The protein encoded by this gene belongs to the delayed rectifier class of channel proteins and is an integral membrane protein that mediates the voltage-dependent potassium ion permeability of excitable membranes. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]

Gene Name: Potassium Voltage-gated Channel Subfamily C Member 2

Chromosome: CHR12: 75433895 -75603511

Locus: 12q21.1

PTPRR Gene Summary

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]

Gene Name: Protein Tyrosine Phosphatase, Receptor Type R

Chromosome: CHR12: 71031852 -71314584

Locus: 12q15

Gene Diseases

The PTPRR KCNC2 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.