PTPRR-NAV3 Fusion FISH Probe
The PTPRR-NAV3 Fusion FISH Probe is used to confirm a fusion of the PTPRR and NAV3 genes. The fusion of the PTPRR and NAV3 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PTPRR-NAV3-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-RERE | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-REOR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-REGO | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-REGR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-REAQ | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-ORRE | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-OROR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-ORGO | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-ORAQ | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GORE | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GOOR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GOGO | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GOGR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GOAQ | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GRRE | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GROR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GRGO | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GRGR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-GRAQ | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-AQRE | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-AQOR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-AQGO | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-AQGR | 20 (40 μL) | 200 μL |
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| PTPRR-NAV3-20-AQAQ | 20 (40 μL) | 200 μL |
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PTPRR Gene Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and a single intracellular catalytic domain, and thus represents a receptor-type PTP. Silencing of this gene has been associated with colorectal cancer. Multiple transcript variants encoding different isoforms have been found for this gene. This gene shares a symbol (PTPRQ) with another gene, protein tyrosine phosphatase, receptor type, Q (GeneID 374462), which is also located on chromosome 12. [provided by RefSeq, May 2011]
Gene Name: Protein Tyrosine Phosphatase, Receptor Type R
Chromosome: CHR12: 71031852 -71314584
Locus: 12q15
NAV3 Gene Summary
This gene belongs to the neuron navigator family and is expressed predominantly in the nervous system. The encoded protein contains coiled-coil domains and a conserved AAA domain characteristic for ATPases associated with a variety of cellular activities. This gene is similar to unc-53, a Caenorhabditis elegans gene involved in axon guidance. Multiple alternatively spliced transcript variants for this gene have been described but only one has had its full-length nature determined. [provided by RefSeq, Jul 2008]
Gene Name: Neuron Navigator 3
Chromosome: CHR12: 78225068 -78606790
Locus: 12q21.2
Gene Diseases
The PTPRR NAV3 Fusion has been associated with the following diseases:
| Disease Name |
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| Sarcoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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