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PUM1-SDCCAG8 Fusion FISH Probe

The PUM1-SDCCAG8 Fusion FISH Probe is used to confirm a fusion of the PUM1 and SDCCAG8 genes. The fusion of the PUM1 and SDCCAG8 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PUM1-SDCCAG8-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-RERE 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-REOR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-REGO 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-REGR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-REAQ 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-ORRE 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-OROR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-ORGO 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-ORAQ 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GORE 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GOOR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GOGO 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GOGR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GOAQ 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GRRE 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GROR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GRGO 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GRGR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-GRAQ 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-AQRE 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-AQOR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-AQGO 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-AQGR 20 (40 μL) 200 μL
PUM1-SDCCAG8-20-AQAQ 20 (40 μL) 200 μL

PUM1 Gene Summary

This gene encodes a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding factor proteins of C. elegans. The encoded protein contains a sequence-specific RNA binding domain comprised of eight repeats and N- and C-terminal flanking regions, and serves as a translational regulator of specific mRNAs by binding to their 3' untranslated regions. The evolutionarily conserved function of the encoded protein in invertebrates and lower vertebrates suggests that the human protein may be involved in translational regulation of embryogenesis, and cell development and differentiation. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]

Gene Name: Pumilio RNA Binding Family Member 1

Chromosome: CHR1: 31404352 -31538564

Locus: 1p35.2

SDCCAG8 Gene Summary

This gene encodes a centrosome associated protein. This protein may be involved in organizing the centrosome during interphase and mitosis. Mutations in this gene are associated with retinal-renal ciliopathy. [provided by RefSeq, Oct 2010]

Gene Name: Serologically Defined Colon Cancer Antigen 8

Chromosome: CHR1: 243419306 -243663393

Locus: 1q43-q44

Gene Diseases

The PUM1 SDCCAG8 Fusion has been associated with the following diseases:

Disease Name
Prostate Adenocarcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.