PUM2-TTLL4 Fusion FISH Probe
The PUM2-TTLL4 Fusion FISH Probe is used to confirm a fusion of the PUM2 and TTLL4 genes. The fusion of the PUM2 and TTLL4 genes has been associated with Liver Hepatocellular Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| PUM2-TTLL4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-RERE | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-REOR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-REGO | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-REGR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-REAQ | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-ORRE | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-OROR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-ORGO | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-ORAQ | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GORE | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GOOR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GOGO | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GOGR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GOAQ | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GRRE | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GROR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GRGO | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GRGR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-GRAQ | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-AQRE | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-AQOR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-AQGO | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-AQGR | 20 (40 μL) | 200 μL |
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| PUM2-TTLL4-20-AQAQ | 20 (40 μL) | 200 μL |
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TTLL4 Gene Summary
The Tubulin Tyrosine Ligase Like 4 (TTLL4) gene is located on chr2 :219575567-219620138 at 2q35.
Gene Name: Tubulin Tyrosine Ligase Like 4
Chromosome: CHR2: 219575567 -219620138
Locus: 2q35
PUM2 Gene Summary
This gene encodes a protein that belongs to a family of RNA-binding proteins. The encoded protein functions as a translational repressor during embryonic development and cell differentiation. This protein is also thought to be a positive regulator of cell proliferation in adipose-derived stem cells. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
Gene Name: Pumilio RNA Binding Family Member 2
Chromosome: CHR2: 20448452 -20527144
Locus: 2p24.1
Gene Diseases
The PUM2 TTLL4 Fusion has been associated with the following diseases:
| Disease Name |
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| Liver Hepatocellular Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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