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PVRL3-KCNMB3 Fusion FISH Probe

The PVRL3-KCNMB3 Fusion FISH Probe is used to confirm a fusion of the PVRL3 and KCNMB3 genes. The fusion of the PVRL3 and KCNMB3 genes has been associated with Mesothelioma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
PVRL3-KCNMB3-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-RERE 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-REOR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-REGO 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-REGR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-REAQ 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-ORRE 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-OROR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-ORGO 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-ORAQ 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GORE 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GOOR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GOGO 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GOGR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GOAQ 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GRRE 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GROR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GRGO 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GRGR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-GRAQ 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-AQRE 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-AQOR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-AQGO 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-AQGR 20 (40 μL) 200 μL
PVRL3-KCNMB3-20-AQAQ 20 (40 μL) 200 μL

KCNMB3 Gene Summary

MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the modulatory beta subunit. The protein encoded by this gene is an auxiliary beta subunit which may partially inactivate or slightly decrease the activation time of MaxiK alpha subunit currents. Alternative splicing results in multiple transcript variants. A related pseudogene has been identified on chromosome 22. [provided by RefSeq, Jul 2009]

Gene Name: Potassium Calcium-activated Channel Subfamily M Regulatory Beta Subunit 3

Chromosome: CHR3: 178957536 -178984838

Locus: 3q26.32

Gene Diseases

The PVRL3 KCNMB3 Fusion has been associated with the following diseases:

Disease Name
Mesothelioma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.