RAB11FIP1-HTRA4 Fusion FISH Probe
The RAB11FIP1-HTRA4 Fusion FISH Probe is used to confirm a fusion of the RAB11FIP1 and HTRA4 genes. The fusion of the RAB11FIP1 and HTRA4 genes has been associated with Breast Invasive Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
|---|---|---|---|---|
| RAB11FIP1-HTRA4-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-RERE | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-REOR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-REGO | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-REGR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-REAQ | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-ORRE | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-OROR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-ORGO | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-ORAQ | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GORE | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GOOR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GOGO | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GOGR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GOAQ | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GRRE | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GROR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GRGO | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GRGR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-GRAQ | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-AQRE | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-AQOR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-AQGO | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-AQGR | 20 (40 μL) | 200 μL |
|
|
| RAB11FIP1-HTRA4-20-AQAQ | 20 (40 μL) | 200 μL |
|
RAB11FIP1 Gene Summary
This gene encodes one of the Rab11-family interacting proteins (Rab11-FIPs), which play a role in the Rab-11 mediated recycling of vesicles. The encoded protein may be involved in endocytic sorting, trafficking of proteins including integrin subunits and epidermal growth factor receptor (EGFR), and transport between the recycling endosome and the trans-Golgi network. Alternative splicing results in multiple transcript variants. A pseudogene is described on the X chromosome. [provided by RefSeq, Dec 2013]
Gene Name: RAB11 Family Interacting Protein 1
Chromosome: CHR8: 37716464 -37757015
Locus: 8p11.23
HTRA4 Gene Summary
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging. [provided by RefSeq, Oct 2008]
Gene Name: HtrA Serine Peptidase 4
Chromosome: CHR8: 38831667 -38846181
Locus: 8p11.22
Gene Diseases
The RAB11FIP1 HTRA4 Fusion has been associated with the following diseases:
| Disease Name |
|---|
| Breast Invasive Carcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
|---|