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RAB11FIP3-RGS11 Fusion FISH Probe

The RAB11FIP3-RGS11 Fusion FISH Probe is used to confirm a fusion of the RAB11FIP3 and RGS11 genes. The fusion of the RAB11FIP3 and RGS11 genes has been associated with Lung Squamous Cell Carcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAB11FIP3-RGS11-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-RERE 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-REOR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-REGO 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-REGR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-REAQ 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-ORRE 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-OROR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-ORGO 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-ORAQ 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GORE 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GOOR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GOGO 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GOGR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GOAQ 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GRRE 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GROR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GRGO 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GRGR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-GRAQ 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-AQRE 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-AQOR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-AQGO 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-AQGR 20 (40 μL) 200 μL
RAB11FIP3-RGS11-20-AQAQ 20 (40 μL) 200 μL

RGS11 Gene Summary

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and four transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2013]

Gene Name: Regulator Of G Protein Signaling 11

Chromosome: CHR16: 318309 -325914

Locus: 16p13.3

RAB11FIP3 Gene Summary

Proteins of the large Rab GTPase family (see RAB1A; MIM 179508) have regulatory roles in the formation, targeting, and fusion of intracellular transport vesicles. RAB11FIP3 is one of many proteins that interact with and regulate Rab GTPases (Hales et al., 2001 [PubMed 11495908]).[supplied by OMIM, Mar 2008]

Gene Name: RAB11 Family Interacting Protein 3

Chromosome: CHR16: 475667 -572481

Locus: 16p13.3

Gene Diseases

The RAB11FIP3 RGS11 Fusion has been associated with the following diseases:

Disease Name
Lung Squamous Cell Carcinoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.