RAB11FIP4-ARHGAP23 Fusion FISH Probe
The RAB11FIP4-ARHGAP23 Fusion FISH Probe is used to confirm a fusion of the RAB11FIP4 and ARHGAP23 genes. The fusion of the RAB11FIP4 and ARHGAP23 genes has been associated with Prostate Adenocarcinoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.
** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.
| SKU | Test Kits | Buffer | Dye Color | Order Now |
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| RAB11FIP4-ARHGAP23-20-ORGR (Standard Design) | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-RERE | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-REOR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-REGO | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-REGR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-REAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-ORRE | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-OROR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-ORGO | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-ORAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GORE | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GOOR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GOGO | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GOGR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GOAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GRRE | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GROR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GRGO | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GRGR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-GRAQ | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-AQRE | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-AQOR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-AQGO | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-AQGR | 20 (40 μL) | 200 μL |
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| RAB11FIP4-ARHGAP23-20-AQAQ | 20 (40 μL) | 200 μL |
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ARHGAP23 Gene Summary
The RHO (see ARHA; MIM 165390) family of small GTPases are involved in signal transduction through transmembrane receptors, and they are inactive in the GDP-bound form and active in the GTP-bound form. GTPase-activating proteins, such as ARHGAP23, inactivate RHO family proteins by stimulating their hydrolysis of GTP (Katoh and Katoh, 2004 [PubMed 15254754]).[supplied by OMIM, Mar 2008]
Gene Name: Rho GTPase Activating Protein 23
Chromosome: CHR17: 36584719 -36668628
Locus: 17q12
RAB11FIP4 Gene Summary
The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the metastatic potential of hepatocellular carcinoma. [provided by RefSeq, Oct 2016]
Gene Name: RAB11 Family Interacting Protein 4
Chromosome: CHR17: 29718641 -29865232
Locus: 17q11.2
Gene Diseases
The RAB11FIP4 ARHGAP23 Fusion has been associated with the following diseases:
| Disease Name |
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| Prostate Adenocarcinoma |
FISH Probe Protocols
| Protocol, Procedure, or Form Name | Last Modified | Download |
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