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RAB21-SLC4A8 Fusion FISH Probe

The RAB21-SLC4A8 Fusion FISH Probe is used to confirm a fusion of the RAB21 and SLC4A8 genes. The fusion of the RAB21 and SLC4A8 genes has been associated with Sarcoma. These probes are FISH confirmed on normal peripheral blood in both interphase nuclei and metaphase spreads before shipment. Typical turnaround time for this product is 7-14 days after purchase.

** This product is for in vitro and research use only. This product is not intended for diagnostic use. Please note that both genes fall on the same chromosome and inter-chromosomal detection may be difficult to detect depending on the genes proximity to one another. Please consult our support staff before ordering this product to ensure that the probe can be designed to meet your specific needs.

Turnaround Time: 7-10 Business Days    Shipping Time: 1-2 Day Expedited Shipping

SKU Test Kits Buffer Dye Color Order Now
RAB21-SLC4A8-20-ORGR  (Standard Design) 20 (40 μL) 200 μL
RAB21-SLC4A8-20-RERE 20 (40 μL) 200 μL
RAB21-SLC4A8-20-REOR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-REGO 20 (40 μL) 200 μL
RAB21-SLC4A8-20-REGR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-REAQ 20 (40 μL) 200 μL
RAB21-SLC4A8-20-ORRE 20 (40 μL) 200 μL
RAB21-SLC4A8-20-OROR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-ORGO 20 (40 μL) 200 μL
RAB21-SLC4A8-20-ORAQ 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GORE 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GOOR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GOGO 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GOGR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GOAQ 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GRRE 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GROR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GRGO 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GRGR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-GRAQ 20 (40 μL) 200 μL
RAB21-SLC4A8-20-AQRE 20 (40 μL) 200 μL
RAB21-SLC4A8-20-AQOR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-AQGO 20 (40 μL) 200 μL
RAB21-SLC4A8-20-AQGR 20 (40 μL) 200 μL
RAB21-SLC4A8-20-AQAQ 20 (40 μL) 200 μL

SLC4A8 Gene Summary

The protein encoded by this gene is a membrane protein that functions to transport sodium and bicarbonate ions across the cell membrane. The encoded protein is important for pH regulation in neurons. The activity of this protein can be inhibited by 4,4'-Di-isothiocyanatostilbene-2,2'-disulfonic acid (DIDS). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Apr 2012]

Gene Name: Solute Carrier Family 4 Member 8

Chromosome: CHR12: 51818593 -51902980

Locus: 12q13.13

RAB21 Gene Summary

This gene belongs to the Rab family of monomeric GTPases, which are involved in the control of cellular membrane traffic. The encoded protein plays a role in the targeted trafficking of integrins via its association with integrin alpha tails. As a consequence, the encoded protein is involved in the regulation of cell adhesion and migration. Expression of this gene is associated with a poor prognosis for glioma patients. This gene is downregulated by the tumor suppressor miR-200b, and miRNA-200b is itself downregulated in glioma tissues. [provided by RefSeq, Nov 2015]

Gene Name: RAB21, Member RAS Oncogene Family

Chromosome: CHR12: 72148657 -72181150

Locus: 12q21.1

Gene Diseases

The RAB21 SLC4A8 Fusion has been associated with the following diseases:

Disease Name
Sarcoma

FISH Probe Protocols

Protocol, Procedure, or Form Name Last Modified Download

Customer Publications

There are currently no FISH related publications for this probe.